My name is Ján Jozef Liener, and I am an 8‑year gymnasium student at the Piaristická spojená škola Františka Hanáka in Prievidza, Slovakia. This year I have the honor of representing my school at the national round of the Biological Olympiad. For my project, I am investigating the epigenetic and anticancer properties of xanthohumol—the main prenylflavonoid derived from spent hops—by optimizing its extraction and characterizing it via HPLC‑MS, followed by in vitro testing on carcinoma cell lines.

A critical component of my study is the use of a high‑purity (≥99%) xanthohumol standard as a control reference for both quantification and cytotoxicity assays. Unfortunately, acquiring this reagent exceeds my personal budget and the modest funds allocated for the competition.

I would be deeply grateful if [Company/Institute Name] could support my project by any of the following means:

 Donation of a small quantity (e.g., 10–20 mg) of ≥99% xanthohumol to serve as a control standard in my HPLC‑MS and cell‑based assays.

 Provision of a discounted academic price for the purchase of ≥99% xanthohumol, allowing me to allocate my limited resources elsewhere.

Your generous assistance would not only enable the rigorous validation of my extraction protocol but also ensure the scientific quality of my competition entry. In return, I would be delighted to acknowledgeECHEMI in all presentations, posters, and any resulting publications.

Thank you very much for considering my request. I am happy to provide any further details about my experimental design, competition timeline, or school credentials at your convenience. I sincerely hope that, with your support, I can advance both my personal learning and contribute meaningful results to the field of natural product epigenetics.

With kind regards and gratitude,

Ján Jozef Liener
Piaristická spojená škola Františka Hanáka, Prievidza